The introductory ode of Horace's fourth book has been given comparatively little critical attention, although it might have been expected to arouse exceptional interest, being the first-fruits of the lyricist's autumnal harvest. The neglect is due partly to the poem's deceptive simplicity but much more to the unease which it arouses in Horace's admirers: Venus does not seem the most fitting deity for the poet laureate to invoke, and moreover this is not so much an invocation as an appeal to (...) be left alone; the young man who is the subject of Horace's eulogy was hardly a person of much eminence at the time of writing, though he became prominent later and is now prosopographically well endowed; above all, there is the disturbing picture of the elderly poet testily acknowledging an amorous urge and surrendering his dignity in pederastic dreams. (shrink)

What is the dry garment which Sceparnio offers to the sea-soaked Charmides? First of all, there is doubt about the spelling of the word. The Palatine tradition is tigillum, though T has tixillum; the Ambrosian palimpsest is provokingly defective at this point and Studemund was unable to determine whether the vowel is e or i. Since the beginning of the sixteenth century editors have chosen to print tegillum, being influenced by notes preserved in the collections of two grammarians—Nonius and Paulus. (...) I quote these from Lindsay's Teubner editions. (shrink)

The reader of Juvenal's fifth satire, making his way through the new Oxford text edited by W. V. Clausen, finds the sweep of the poet's indignant rhetoric interrupted by the obeli of 104. Reference to Clausen's paper which he quotes in support of his proposed reading glaucis sparsus reveals that he proceeds from the assumption that the line is corrupt, and evidence that this is the case must be sought elsewhere.

Intent and mitigating circumstances play a central role in moral and legal assessments in large-scale industrialized societies. Al- though these features of moral assessment are widely assumed to be universal, to date, they have only been studied in a narrow range of societies. We show that there is substantial cross-cultural variation among eight traditional small-scale societies (ranging from hunter-gatherer to pastoralist to horticulturalist) and two Western societies (one urban, one rural) in the extent to which intent and mitigating circumstances influence (...) moral judgments. Although participants in all societies took such factors into account to some degree, they did so to very different extents, varying in both the types of considerations taken into account and the types of violations to which such considerations were applied. The particular patterns of assessment characteristic of large-scale industrialized societies may thus reflect relatively recently culturally evolved norms rather than inherent features of human moral judgment. (shrink)

MEDIEVAL LOGICS LAMBERT MARIE DE RIJK (ed.), Die mittelalterlichen Traktate De mod0 opponendiet respondendi, Einleitung und Ausgabe der einschlagigen Texte. (Beitrage zur Geschichte der Philosophie und Theologie des Mittelalters, Neue Folge Band 17.) Miinster: Aschendorff, 1980. 379 pp. No price stated. THE SEVENTEENTH CENTURY MARTA FATTORI, Lessico del Novum Organum di Francesco Bacone. Rome: Edizioni dell'Ateneo 1980. Two volumes, il + 543, 520 pp. Lire 65.000. VIVIAN SALMON, The study of language in 17th century England. (Amsterdam Studies in the Theory (...) and History of Linguistic Science, Series 111: Studies in theHistory of Linguistics, Volume 17.) Amsterdam: John Benjamins B.V., 1979.x + 218 pp. Dfl. 65. Theoria cum Praxi. Zum Verhaltnis von Theorie und Praxis im 17. und 18. Jahrhundert. (Akten des 111. Internationalen Leibnizkongress, Hannover, 12. bis 17.November 1977, Band 111: Logik, Erkenntnistheorie, Wissenschaftstheorie, Metaphysik, Theologie.) Wiesbaden: Franz Steiner Verlag, 1980. vii + 269 pp. DM 48. CLASSICAL AND NON-CLASSICAL LOGICS MICHAEL CLARK, The place of syllogistic in logical theory. Nottingham: University of Nottingham Press, 1980. ix + 151 pp. £3.00. A.F. PARKER-RHODES, The theory of indistinguishables. Dordrecht, Boston and London: D. Reidel Publishing Company, 1981. xvii + 216 pp. Dfl.90.00/$39.50. NICHOLAS RESCHER and ROBERT BRANDOM, The logic of inconsistency. Oxford:Basil Blackwell, 1980. x + 174 pp. f 11.50. MISCELLANEOUS J. ZELENY, The logic of Marx. Translated from the German by T. Carver. Oxford: Basil Blackwell, 1980. xcii + 247 pp. £12.50. FELIX KAUFMANN, The infinite in mathematics. Edited by Brian McGuinness. Introduction by E. Nagel. Translation from the German by Paul Foulkes. Dordrecht: Reidel, 1978. xvii + 235 pp. Dfl 85/$39.50 (cloth); Dfl 45/$19.95 (paper). PAMELA MCCORDUCK, Machines who think. San Francisco: W.H. Freeman and Company, 1979. xiv + 275 pp. $14.95. J. MITTELSTRASS (ed.), Enzyklopadie Philosophie und Wissenschaftstheorie Bd. 1 : A-G. Mannheim, Wien, Ziirich: Bibliographisches Institut, 1980. 835 pp. DM 128. (shrink)

We examined if cancer patients' health-related quality of life (HRQoL) scores on the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 are affected by the specific time point, before or during treatment, at which the questionnaire is completed, and whether this could bias the overall treatment comparison analyses. A 'completion-time window' variable was created on three closed EORTC randomised control trials in lung (non-small cell lung cancer, NSCLC) and colorectal cancer (CRC) to indicate when the QLQ-30 was completed (...) relative to chemotherapy cycle dates, defined as 'before', 'on' and 'after'. HRQoL mean scores were calculated using a linear mixed model. Statistically significant differences (P < 0.05) were observed on 6 and 5 scales for 'on' and 'after' comparisons in the NSCLC and two-group CRC trial, respectively. As for the three-group CRC trial, several statistical differences were observed in the 'before' to 'on' and the 'on' to 'after' comparisons. For all three trials, including the 'completion-time window' variable in the model resulted in a better fit, but no substantial changes in the treatment effects were noted. We showed that considering the exact timing of completion within specified windows resulted in statistical and potentially clinically significant differences, but it did not alter the conclusions of treatment comparison in these studies. (shrink)

Five percent of all human tumors are found in the head and neck region with an increasing rate. Head and neck tumors are not only a significant problem because of the large number of people affected. The functional and cosmetic disadvantages and stigmas related to the therapy influence the medical recommendations for each individual patient.

Several lines of evidence suggest that children born via Cesarean section are at greater risk for adverse health outcomes including allergies, asthma and obesity. Vaginal seeding is a medical procedure in which infants born by C-section are swabbed immediately after birth with vaginal secretions from the mother. This procedure has been proposed as a way to transfer the mother's vaginal microbiome to the child, thereby restoring the natural exposure that occurs during vaginal birth that is interrupted in the case of (...) babies born via C-section. Preliminary evidence indicates partial restoration of microbes. However, there is insufficient evidence to determine the health benefits of the procedure. Several studies, including trial, are currently underway. At the same time, in the clinic setting, doctors are increasingly being asked to by expectant mothers to have their babies seeded. This article reports on the current research on this procedure and the issues it raises for regulators, researchers, physicians, and patients. (shrink)

The spatial dynamics of the optical emission from an array of 50 times 50 individual microcavity plasma devices is investigated. The array is operated in argon and argon-neon mixtures close to atmospheric pressure with an ac voltage. The optical emission is analysed with phase and space resolution. It has been found that the emission is not continuous over the entire ac period, but occurs once per half period. Each of the observed emission phases shows a self-pulsing of the discharge, with (...) several bursts of emission of fixed width and repetition rate. The number of emission bursts depends on applied voltage and frequency. Spatially resolved measurements prove that the emission bursts are formed by overlapping emission pulses from single discharge cavities. Intensity differences between positive and negative half-wave can be interpreted through spatially resolved measurements of single discharge cavities. (shrink)

Human moral judgement may have evolved to maximize the individual's welfare given parochial culturally constructed moral systems. If so, then moral condemnation should be more severe when transgressions are recent and local, and should be sensitive to the pronouncements of authority figures (who are often arbiters of moral norms), as the fitness pay-offs of moral disapproval will primarily derive from the ramifications of condemning actions that occur within the immediate social arena. Correspondingly, moral transgressions should be viewed as less objectionable (...) if they occur in other places or times, or if local authorities deem them acceptable. These predictions contrast markedly with those derived from prevailing non-evolutionary perspectives on moral judgement. Both classes of theories predict purportedly species-typical patterns, yet to our knowledge, no study to date has investigated moral judgement across a diverse set of societies, including a range of small-scale communities that differ substantially from large highly urbanized nations. We tested these predictions in five small-scale societies and two large-scale societies, finding substantial evidence of moral parochialism and contextual contingency in adults' moral judgements. Results reveal an overarching pattern in which moral condemnation reflects a concern with immediate local considerations, a pattern consistent with a variety of evolutionary accounts of moral judgement. (shrink)

This paper is a preliminary inquiry into the nature of implication; how things are seen as ‘going together’ or following one from another. The argument presented here is that implication is non-logical and is central to the routine process of reason, induction and generalization. The organizing force underlying implication and practical inference is argued to be Von Domarus’ Principle , by which similarity on some dimension of interest ‘carries over’ to some other dimension of interest.One major difficulty with this formulation (...) is that where VDP is the only organizing force, incoherent utterances resembling the word salad of the schizophrenic are likely to result, quite a departure from the routine utterances of normals that a useful model should generate. Two important ways that normal speech and word salad differ are that, in the latter, associations are, first, often implausible or bizarre, and second, they are likely to be so personalistic as to be virtually inaccessible to others.These considerations led to a search for elements that would provide the corrections necessary to bring the products of a VDP based model of implication close to normal utterances in these two areas. One element that appears central, concerns the role of subjective probability in evaluating plausibility of associations. Also considered are aspects of ambiguities in ordinary language especially concerning number and probability. The problem of making associations accessible to others is mitigated by providing elements in the setting or the communication itself that act to highlight or salience the association intended to be communicated. Finally, suggestions for further research are presented. (shrink)

Every student of the twentieth century has heard both of the great Viennese economist Friedrich von Hayek and of the equally great philosopher Ludwig Wittgenstein. But what isn't well known is that the two were distant cousins and that, shortly after Wittgenstein's death in 1951, Hayek set out to write a biography of his cousin. The project was derailed by Wittgenstein family members, who felt it was to soon to publish such a work - especially one like Hayek's, so candid (...) about his cousin's difficulties and depressions. But Hayek's draft acquired an underground readership, and Wittgensteins biographers have used it extensively. Here finally, is the text of that work itself - a true goldmine in being one great thinker's view of another, whom he knew personally, even if not well. Hayek's account has the great merit of being close to its subject; the draft, moreover sheds light, not only on Wittgenstein but on Hayek as well. (shrink)

T × W logic is a combination of tense and modal logic for worlds or histories with the same time order. It is the basis for logics of causation, agency and conditionals, and therefore an important tool for philosophical logic. Semantically it has been defined, among others, by R. H. Thomason. Using an operator expressing truth in all worlds, first discussed by C. M. Di Maio and A. Zanardo, an axiomatization is given and its completeness proved via D. Gabbay’s irreflexivity (...) lemma. Given this lemma the proof is more or less straight forward. At the end an alternative axiomatization is sketched in which Di Maio’s and Zanardo’s operator is replaced by a version of “actually”. (shrink)

The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to significantly advance medical knowledge. However, sharing of such resources for international collaboration is hampered by the lack of clarity about ethical and legal requirements for transfer of data and samples across international borders. Here, the International Clinical Trial Center Network reports the legal and ethical requirements governing data and sample exchange (...) across four continents. The most recurring requirement is ethical approval, whereas only in specific conditions approval of national health authorities is required. Informed consent is not required in all sharing situations. However, waiver of informed consent is only allowed in certain countries/regions and under certain circumstances. The current legal and ethical landscape appears to be very complex and under constant evolution. Regulations differ between countries/regions and are often incomplete, leading to uncertainty. With this work, ICN illuminates the unmet need for a single international collaborative framework to facilitate DSE. Harmonising requirements for global DSE will reduce inefficiency and waste in research. There are many challenges to realising this ambitious vision, including inconsistent terminology and definitions, and heterogeneous and dynamic legal constraints. Here, we identify areas of agreement and significant difference as a necessary first step towards facilitating international collaboration. We propose the establishment of a working group to continue the comparison across jurisdictions, create a standardised glossary and define a set of basic principles and fundamental requirements for DSE. (shrink)

Newman’s defense of the role of the laity in the development of doctrine not only occasioned a negative reaction from the Vatican, it had continued reverberations among his followers.This essay examines Newman’s influence on Baron Friedrich von Hügel and then compares the Baron’s positions with those Newman’s biographer, Wilfred Ward.

This article contains a brief critique of von Kutschera's conception of God, especially of the conceptual tension between divine transcendence and divine personhood, and of his response to the problem of evil.

Context: The enactive paradigm in the cognitive sciences is establishing itself as a strong and comprehensive alternative to the computationalist mainstream. However, its own particular historical roots have so far been largely ignored in the historical analyses of the cognitive sciences. Problem: In order to properly assess the enactive paradigm’s theoretical foundations in terms of their validity, novelty and potential future directions of development, it is essential for us to know more about the history of ideas that has led to (...) the current state of affairs. Method: The meaning of the disappearance of the field of cybernetics and the rise of second-order cybernetics is analyzed by taking a closer look at the work of representative figures for each of the phases: Rosenblueth, Wiener and Bigelow for the early wave of cybernetics, Ashby for its culmination, and von Foerster for the development of the second-order approach. Results: It is argued that the disintegration of cybernetics eventually resulted in two distinct scientific traditions, one going from symbolic AI to modern cognitive science on the one hand, and the other leading from second-order cybernetics to the current enactive paradigm. Implications: We can now understand that the extent to which the cognitive sciences have neglected their cybernetic parent is precisely the extent to which cybernetics had already carried the tendencies that would later find fuller expression in second-order cybernetics. (shrink)

Bruce Caldwell has disputed a number of points in my earlier account of the development of the Austrian school of economics from Carl Menger to Ludwig von Mises and F.A. Hayek. The issues in contention regard Friedrich von Wieser’s intellectual affiliation with Hayek and his influence on the formation of Hayek’s economic thought; Wieser’s status as a general equilibrium theorist; and the reason for Hayek’s early flirtation with general equilibrium theory. In this article I argue that Hayek was a self-conscious (...) adherent of the Wieserian tradition and remained so even after he received the Nobel Prize in 1974 and that he distinguished between this tradition and the Böhm-Bawerkian tradition followed by Ludwig von Mises. I also contend that Wieser used the construction of a general equilibrium economy subject to a single will as both a normative benchmark by which to appraise the performance of the real-world market economy and as an analytical tool to explain the formation of market prices. Finally, I argue that Hayek concerned himself with the problems of the Wieser-type general equilibrium economy beginning with his earliest writings as a professional economist, years before he began to focus on the theoretical problems of money and the business cycle.Bruce Caldwell a discuté un certain nombre de points de mon article récent sur le développement de l’école autrichienne d’économie de Carl Menger en passant par Ludwig von Mises et F.A. Hayek. Les controverses concernant l’affiliation intellectuelle de Hayek vis-à-vis de Friedrich von Wieser et l’influence de ce dernier sur la pensée économique de Hayek, le statut de Wieser en tant que théoricien de l’équilibre général, et les raisons pour lesquelles le jeune Hayek flirta avec la théorie de l’équilibre général.Dans cet article je défends la thèse selon laquelle Hayek était conscient du fait qu’il s’inscrivait dans la tradition Wieserienne et qu’il l’était toujours même après sa réception du prix Nobel en 1974 et quand il fît la distinction entre cette tradition et la tradition inaugurée par Böhm-Bawerk et poursuivie par Mises. L’article affirme aussi que Wieser utilisa la construction d’une économie en équilibre général sujette à une volonté unique à la fois comme standard normatif pour évaluer les performances des marchés dans le monde réel et comme outil analytique pour expliquer la formation des prix marchands. Enfin, l’article argumente que Hayek s’intéressa aux problèmes relevant d’une économie en équilibre général à la Wieser dans ses premiers écrits en tant qu’économiste et cela bien avant qu’il ne se concentrât sur les problèmes théoriques de la monnaie et du cycle des affaires. (shrink)

An analysis is presented of the significance and consequent limitations on the applicability of the von Neumann measurement postulate in quantum mechanics. Directly observable quantities, such as the expectation value of the velocity operator, are distinguished from mathematical constructs, such as the expectation value of the canonical momentum, which are not directly observable. A simple criterion to distinguish between the two types of operators is derived. The non-observability of the electromagnetic four-potentials is shown to imply the non-measurability of the canonical (...) momentum. The concept of a mechanical gauge is introduced and discussed. Classically the Lagrangian is nonunique within a total time derivative. This may be interpreted as the freedom of choosing a “mechanical” (M) gauge function. In quantum mechanics it is often implicitly assumed that the M-gauge vanishes. However, the requirement that directly observable quantities be independent of the arbitrary mechanical gauge is shown to lead to results analogous to those derived from the requirement of electromagnetic gauge independence of observables. The significance of the above to the observability of transition amplitudes between field-free energy eigenstates in the presence (and absence) of electromagnetic fields is discussed. E- and M-gauge independent transition amplitudes between field-free energy eigenstates in the absence of electromagnetic fields are defined. It is shown that, in general, such measurable amplitudes cannot be defined in the presence of externally applied time-dependent fields. Transition amplitudes in the presence of time-independent fields are discussed. The path dependence of previous derivations of E-gauge independent Hamiltonians and/or transition amplitudes in the presence of electromagnetic fields are related to the inherent M-gauge dependence of these quantities in the presence of such fields. (shrink)

Our immediate intuition about (1) is that –ever indicates speaker’s ignorance. We hear the speaker as signaling that she doesn’t know what Arlo is cooking, while at the same time asserting that no matter what Arlo is cooking, there’s a lot of garlic in it. The FR without –ever in (2) carries no such signal of ignorance.

Ausgehend von einer Kritik an der Kultur der Aufklärung entwickelt Friedrich Schiller eine Anthropologie echter idealistischer Denkungsart. In seiner ästhetischen Lehre vom Menschen spürt er den Bedingungen der Möglichkeit von Freiheit und Humanität nach und entdeckt in der Schönheit die Voraussetzung einer jeden Bildung. Mittels einer transzendentalen Explikation wird in der vorgelegten Studie Schillers anthropologischer Entwurf kritisch geprüft und der Zusammenhang von Schönheit, Freiheit und Bildung philosophisch entfaltet. Auf diese Weise kann die ungebrochene Bedeutung ästhetischen Denkens für die Pädagogik der (...) Gegenwart aufgezeigt werden"--Back cover. (shrink)

This is the second article in a series of review articles addressing biosemiotic terminology. The biosemiotic glossary project is designed to integrate views of members within the biosemiotic community based on a standard survey and related publications. The methodology section describes the format of the survey conducted July–August 2014 in preparation of the current review and targeted on Jakob von Uexküll’s term ‘Umwelt’. Next, we summarize denotation, synonyms and antonyms, with special emphasis on the denotation of this term in current (...) biosemiotic usage. The survey findings include ratings of eight citations defining or making use of the term Umwelt. We provide a summary of respondents’ own definitions and suggested term usage. Further sections address etymology, relevant contexts of use, and related terms in English and other languages. A section on the notion’s Uexküllian meaning and later biosemiotic meaning is followed by attempt at synthesis and conclusion. We conclude that the Umwelt is a centerpiece phenomenon, a phenomenon that other phenomena in the living realm are organized around. To sum up Uexküll’s view, we can characterize an Umwelt as the subjective world of an organism, enveloping a perceptual world and an effector world, which is always part of the organism itself and a key component of nature, which is held together by functional cycles connecting different Umwelten. In order to pay respect to Uexküll’s work, we must move from notion to model, from mention of Uexküll’s Umwelt term to actual application of it. (shrink)

À propos du cas de Henriette D. Les femmes et l'enfermement psychiatrique dans la France du XXe siècle. Née en 1887 et internée en 1925, Henriette D., dont nous avons pu consulter le dossier médical, a séjourné à l’hôpital psychiatrique du Vinatier (Lyon/Bron) jusqu’à sa mort en 1999. Soit pendant près de trois-quarts de siècle. Quelles sont les causes de son internement? Pourquoi a-t-elle été maintenue si longtemps à l’asile, y compris dans une période (à partir des années 1960-1970) où (...) la désinstitutionalisation et le « maintien dans la communauté » sont devenus les maîtres mots de la prise en charge des malades mentaux? Formulées à partir d’un itinéraire de patient, ces interrogations conduisent à poser la question du genre à l’hôpital psychiatrique au XXe siècle. Et donc à poser en d’autres termes la question des rapports que la société entretient avec la folie. (shrink)

Note du traducteur: La transcription rend fidèlement l’orthographe de l’inédit autographe de Helmholtz, et cela jusqu’à l’oubli du « t » dans le mot « nicht », erreur que l’auteur ne semble pas avoir remarquée ou à laquelle il ne devait pas accorder d’importance, vu qu’il s’agissait, probablement, d’une ébauche très avancée du rapport qui aurait dû, ou pu, être copiée, après correction, pour l’envoi en Italie.Dans la transcription ainsi que dans la traduction, l’espace laissé en blanc d’une...

This article contends that Hans Urs von Balthasar's theological focus on seeing the form of God's glory in creation constitutes a critical resource for elaborating a contemporary Christian theology responsive to the crisis of environmental degradation. In particular, in this article Martin Heidegger's reflections on the environmental dangers present in modern technology provide the framework for analyzing the ecological significance of Balthasar's retrieval of a Christian sacramental ontology.